Molecular markers for colorectal cancer screening
نویسندگان
چکیده
منابع مشابه
Fecal Molecular Markers for Colorectal Cancer Screening
Despite multiple screening techniques, including colonoscopy, flexible sigmoidoscopy, radiological imaging, and fecal occult blood testing, colorectal cancer remains a leading cause of death. As these techniques improve, their sensitivity to detect malignant lesions is increasing; however, detection of precursor lesions remains problematic and has generated a lack of general acceptance for thei...
متن کاملMolecular screening testing for colorectal cancer.
Worldwide, colorectal cancer is diagnosed in f1 million individuals each year, accounting for >9% of all new cancer cases (1). Approximately 529,000 people worldwide die of this disease annually. In 2006, it is estimated that 146,000 cases of colorectal cancer will occur in the United States with 55,000 deaths (2). Colorectal cancer is an excellent candidate for population-based screening becau...
متن کاملImportant molecular genetic markers of colorectal cancer
Colorectal cancer (CRC) ranks third in the incidences of cancer morbidity and mortality worldwide. CRC is rather heterogeneous with regard to molecular genetic characteristics and pathogenic pathways. A wide spectrum of biomarkers is used for molecular subtype determination, prognosis, and estimation of sensitivity to different drugs in practice. These biomarkers can include germline and somati...
متن کاملRole of Molecular Biomarkers in Colorectal Cancer
Colorectal cancer (CRC) is amongst the most widespread cancers and is a most common cause of cancer associated mortality universally. Since previous decades, it has been cleared that CRC develops owing to the buildup of a series of genetic and epigenetic changes in the normal colonic epithelium. Regardless of the current development in surgery and therapies, overall survival of end stage CRC pa...
متن کاملScreening for colorectal cancer
Colorectal cancer is an ideal disease to be screened. It is the second most common cancer after lung and is the most common fatal malignancy in non-smokers. Colorectal cancer arises from a benign process, an adenoma or a polyp. A polyp is probably present for 10-20 years before it becomes malignant. Not all polyps become cancerous and it is not possible to predict with certainty which ones carr...
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ژورنال
عنوان ژورنال: Gut
سال: 2015
ISSN: 0017-5749,1468-3288
DOI: 10.1136/gutjnl-2014-308075